San Francisco 49ers tight end George Kittle was ruled inactive for his second straight game Sunday against the visiting Seattle Seahawks.
The 49ers star sustained a groin injury during a Sept. 5 practice session and did not return to practice until Friday, in a limited capacity.
Kittle, 28, caught 71 passes for 910 yards and six touchdowns in 14 starts last season.
The three-time Pro Bowl selection has not played a full season since 2018 due to various injuries.
Quarterback Brock Purdy, defensive lineman Kemoko Turay and offensive linemen Nick Zakelj and Daniel Brunskill were listed as inactive versus the Seahawks.